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12 Diseases Which Are So Mysterious Even Doctors Couldn’t Explain Them

By KK Angus, 10 March 2018


Not every disease is under the grasp of medical science. This may sound too scary to be true, but that is the case. Several curious conditions and disorders have killed people all over the world, and yet doctors have not been able to come to conclusions about their causes or even their symptoms. If it sounds like a frightening sci-fi movie, then buckle up. We are telling you about some of the most mysterious diseases which doctors have not been able to figure out.



An extremely rare mutation where muscles and tendons are replaced by bones. A person suffering from Fibrodysplasia will have an excess of bone tissues which will obviously restrict their movement and eventually the person won't be able to move at all. This condition could also be fatal and there are no certified treatments for this.


Image Source: TN.com

2Encephalitis lethargica


Also known as sleepy sickness this condition leads to some terrible neurological disorders. This disease reached an epidemic like phase between 1915 to 1917. Its symptoms are a sore throat, weakness and the person can fall asleep anywhere at anytime. Adolf Hitler once reportedly suffered from Encephalitis lethargica.

Encephalitis lethargic

Image Source: altervista.org

3Exploding head syndrome


This might sound like a syndrome from a comedy movie but this ailment is quite terrible. A person affected by Exploding Head syndrome will hear loud, imagined noises around him, like explosions or gunshots. Doctors from all over the world have never been able to fully dissect why this syndrome occurs.

Exploding head syndrome

Image Source: www.rebelcircus.com

4Stiff person syndrome


A very rare neurological disorder which is characterized by unusual stiffness and rigidness. In fact, at times the muscles just refuse to respond to reflexes and turn incredibly stiff causing the body to get paralyzed.

Stiff person syndrome

Image Source: aibolita.com


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